White wavy lines texture on a surfaceAcetyl Tetrapeptide-11

Acetyl Tetrapeptide-11

Commonly known as: Acetyl Tetrapeptide-11, AcTP2.
I.N.C.I. list name: Acetyl Tetrapeptide-11.
Extraction process: Chemical synthesis of peptides followed by N-acetylation.
Source: Synthetic.
Botanical name: /
Family: /
Part of the plant extracted: /
Provenance, origin: United States.
Chemical characteristics: Amino acid sequence: proline-proline-tyrosine-leucine; Molecular weight: 530.6 g/mol; Soluble in water; Insoluble in oil.
Characteristics: Colloidal solution, emulsion, true hydrophilic solution, suspension, foam.
Dosage required in cosmetic products: From 2 to 10%.
Function: Skin maintenance agent.
Properties: Densifying, firming, regenerating.
Benefits: All skin types, and particularly mature skin.

Details

Properties

  • Firming: Strengthening the weakened cohesion between the dermis and epidermis by stimulating the synthesis of collagen and syndecan, a membrane protein that contributes to cell proliferation, cell migration, and cell-matrix interactions;

  • Densifying, regenerating: Increasing cellular density by stimulating the proliferation of epidermal keratinocytes.

Usage

  • Facial Care(creams, serums, eye contours);

  • Hair Care (shampoos, serums, styling foams);

  • Makeup (foundation).

Method of Preservation

Keep it protected from light, moisture, and heat.

Contraindications, Usage Precautions

The acetyl tetrapeptide-11 is very well tolerated by the epidermis and does not present any health risks, due to the use of minimal doses that represent only a very small percentage of the final formulation.

Find out more

Acetyl Tetrapeptide-11 is a synthetic signal peptide, produced by acetylation between acetic acid and Tetrapeptide-11. Peptides have the ability to penetrate deep layers of the skin to give various commands to skin cells. Specifically, Acetyl Tetrapeptide-11 can increase the synthesis of the proteoglycan, syndecan-1, to strengthen the cohesion of the epidermis, improve the structural integrity of the dermo-epidermal junction (epidermal basal membrane), as well as the cohesion between the epidermis and the dermis that is altered by aging by stimulating the production of collagen by dermal fibroblasts. It also stimulates the proliferation of keratinocytes, which increases cell density.