Biotinyl-GHK
Is biotinyl-GHK compatible with color-treated hair?
Yes, biotinyl-GHK is safe for color-treated hair and does not affect its color.
Is biotinyl-GHK safe for daily use?
Yes, biotinyl-GHK is generally well tolerated and can be used daily in hair and skin care.
Is biotinyl-GHK effective against hair loss?
Yes, this peptide is recognized for its ability to reduce hair loss by strengthening hair follicles.
What is the difference between biotinyl-GHK and biotin?
Biotinyl-GHK is the product of the reaction between biotin (vitamin B8) and tripeptide-1, a peptide composed of three amino acid residues: glycine, histidine, and lysine (Gly-His-Lys).
Can biotinyl-GHK be used on eyelashes and eyebrows?
Yes, certain products formulated to boost eyelash and eyebrow growth contain biotinyl-GHK.
How does biotinyl-GHK act on the hair follicle?
This peptide stimulates the proliferation of follicular dermal papilla cells, which are essential for hair growth. It promotes cell proliferation by activating signaling pathways such as the extracellular signal–regulated kinase (ERK1/2) pathway, enhancing ERK1/2 phosphorylation. This activation leads to increased expression of genes involved in hair regeneration, including vascular endothelial growth factor (VEGF), fibroblast growth factor-2 (FGF-2), and fibroblast growth factor-7 (FGF-7), all of which support the growth of scalp and body hair.
Can biotinyl-GHK cause ocular irritation?
Eyelash formulations are engineered to mitigate this risk. However, individual sensitivity remains possible, underscoring the importance of avoiding direct contact with the eye.
Can biotinyl-GHK be combined with other hair-active ingredients?
Yes, biotinyl-GHK is frequently combined with other peptides or vitamins. These combinations are intended to deliver complementary effects on the follicle and the fiber.
Is it possible to use products containing biotinyl-GHK during pregnancy?
There are no specific contraindications linked to biotinyl-GHK during pregnancy. However, as a precaution, it is still advisable to seek medical advice.
At what concentration is it used?
Biotinyl-GHK is typically used at concentrations ranging from 1% to 3%.
