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Quand utiliser l'acide mandélique ?

When to use mandelic acid?

Mandelic acid, known by the INCI name "Mandelic acid", is an AHA. It is derived from bitter almonds. This fruit acid can be of natural or synthetic origin. It is valued for its benefits to the skin and hair. If you are considering incorporating a treatment containing this acid into your beauty routine, here is what you need to know.

Published on February 13, 2023, updated on March 26, 2026, by Stéphanie, PhD, Doctorate in Life and Health Sciences — 4 min of reading

Mandelic acid, a solution to certain targeted issues.

What is Mandelic Acid?

Mandelic acid (INCI name: Mandelic Acid) is the largest of the AHAs (alpha-hydroxy acids), derived from the hydrolysis of bitter almonds. It is very gentle and non-irritating, and due to its high molecular weight, it penetrates less deeply into the epidermis than other AHAs, acting on the surface. This fruit acid, known for its keratolytic action, gently removes dead cells accumulated on the surface of the epidermis that dull the complexion, give an irregular appearance to the skin texture, and are responsible for the appearance of imperfections.

The benefits of mandelic acid on the skin.

  • Anti-blemish: Anti-microbial and anti-inflammatory, the use of mandelic acid skincare helps control bacterial proliferation, unclog pores, and reduce inflammation. This, in turn, helps to smooth out irregularities and prevent future skin breakouts.

  • Combating the signs of aging: Regenerative, mandelic acid promotes cellular renewal, which helps to act on the signs of aging, particularly by reducing the appearance of fine lines and improving skin elasticity.

  • Radiance and complexion uniformity: with its exfoliating power, mandelic acid evens out the complexion, helps to restore radiance to the epidermis, and reduces the appearance of pigmented spots.

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Mandelic Acid: When to Properly Incorporate it into Your Skincare Routine?

Photosensitizing, potentially irritating, redness... the use of mandelic acid must be reasonable and controlled, even though it is considered mild and suitable for most skin types.

When is the best time of day to use mandelic acid?

Skincare products containing mandelic acid should be applied only in the evening to maximize their effects and minimize the risk of irritation and photosensitivity. Indeed, AHAs, including mandelic acid, increase photosensitivity because they reduce the natural photoprotection provided by the stratum corneum, which can lead to sunburn. Therefore, it is safer to apply skincare products containing AHAs at bedtime.

Furthermore, the night corresponds to the time when the skin initiates its natural regeneration process: this is when it will be most receptive to exfoliation and to the cellular renewal stimulation induced by mandelic acid.

Nevertheless, cleansing treatments with a low concentration of mandelic acid (< 5%) can also be used in the morning. Additionally, the surfactants present in the product will eliminate the mandelic acid molecules.

In all instances, it is crucial not to forget to adequately protect oneself against UV rays by applying a product with a sun protection factor (SPF) at the end of one's morning routine.

How often should mandelic acid be used?

The frequency of use for a mandelic acid skincare product depends on the concentration of free acids. At a moderate concentration (> 8%), mandelic acid can be tolerated for bi-weekly application. However, at a lower concentration (< 8%), it can be used daily, depending on your skin's tolerance level.

In all instances, it is advisable to start a skincare regimen with mandelic acid progressively. Serum, lotion, night cream..., for daily skincare products, start by applying them once or twice a week to acclimate your skin.

Furthermore, treatments with a high concentration of mandelic acid are generally recommended for use in a regimen of a few weeks or months until the desired results are achieved. It is possible to resume its use several months or years later if you wish.

For the initial use of a new mandelic acid skincare product, please read and follow the manufacturer's instructions to ensure safe use and minimize the risk of irritation.

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