Tobacco and skin: the misconceptions.

Yes and no. It's important to understand that after quitting smoking, certain aspects of your skin will improve. Indeed, Kohei TAKAHASHI and his team demonstrated in a study that quitting smoking for four weeks could increase skin clarity and reduce redness, by lowering the level of hemoglobin in the blood.

However, another study, conducted by Finn GOTTRUP and his colleagues, concluded that the impairment of healing capacity caused by smoking could be long-lasting, if not irreversible. Parameters such as transepidermal water loss, which is high for smokers and should decrease during normal healing, did not show a significant difference between active smokers and former smokers, particularly in terms of the time evolution of this measure.

However, these are only hypotheses, underscoring the need for additional studies.

Yes. In 2009, Mauro PICARDO and his team demonstrated a correlation between the frequency of non-inflammatory acne and smoking. Smoking appears to increase oxidative stress, thereby generating free radicals, and decrease levels of vitamin E in the plasma, which is the main antioxidant transported by sebum to the skin's surface to maintain a low rate of lipid peroxidation in the sebaceous glands, such as squalene. When peroxide of this is produced, it exerts a hyper-proliferative effect on keratinocytes, which will clog the pores and thus be comedogenic. In this way, smoking can cause the onset of acne.

No. This idea is quite widespread, due to the fact that many skin-related consequences of smoking have been perceived as dose-dependent in relation to the quantity of cigarettes smoked. However, several studies have reported significant effects on the skin from light smoking.

For instance, Enrico Maria PROCACCINI and his colleagues found that smoking just one cigarette can affect the skin's microcirculation by reducing blood flow. This will then impact cellular renewal. An accumulation of dead cells on the skin will be observed, followed by a dulling of the complexion.

No. Secondhand smoke, that is, the involuntary inhalation of smoke emitted by one or more smokers, can also have harmful effects on the skin. Indeed, tobacco smoke alone contains approximately 1,017 free radicals per puff, which if inhaled, can cause skin damage by oxidizing dermal fibers such as collagen and elastin, thereby accelerating skin aging. This will also induce the secretion of pro-inflammatory cytokines like IL-12, which consequently leads to the onset of inflammatory conditions such as psoriasis.

This smoke also contains toxic compounds, such as nitrosamines, phenolic compounds, and aromatic amines. These substances can cause DNA mutations and lead to skin cancers. Finally, it contains nicotine, carbon monoxide, and hydrogen cyanide, which interfere with the processes involved in wound healing and thus will impact scar formation.