The coconut oil is renowned for its antimicrobial and soothing properties, largely attributed to its high medium-chain fatty acid content, particularly lauric acid. In the virgin coconut oil, this fatty acid can represent approximately 45 to 52% of the lipid composition. Lauric acid can be transformed by certain enzymes, lipases, into several derivatives, including monolaurin, compounds that exhibit both hydrophilic and lipophilic properties and are recognized for their antimicrobial activity.
Several experimental studies have shown that lauric acid and monolaurin display a broad-spectrum antibacterial, antifungal, and antiviral activity. They are notably capable of disrupting the membrane integrity of certain microorganisms, contributing to the inactivation of Gram-positive bacteria such as Staphylococcus aureus, yeasts such as Candida albicans, as well as enveloped viruses, including herpes simplex virus (HSV) and vesicular stomatitis virus (VSV). This membrane-disrupting capacity represents one of the primary antimicrobial mechanisms of coconut oil.
It is in this context that the hypothesis of coconut oil having an effect on warts emerged. As a reminder, warts are caused by the human papillomavirus (HPV), a skin-tropic virus. However, unlike lipid-enveloped viruses sensitive to monolaurin, HPV lacks a lipid envelope, which theoretically limits the antiviral potential of coconut oil. Furthermore, in the absence of available data on the potential antiviral effects of coconut oil against HPV, it is difficult to assess its efficacy against warts.
Thus, while the biochemical composition of coconut oil suggests antimicrobial potential, its usefulness in the management of warts remains to be confirmed through clinical studies.