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Acide hyaluronique et pores dilatés

Enlarged Pores: Is Hyaluronic Acid a Solution?

Dilated pores, while not aesthetically pleasing, disrupt the uniformity of the skin's texture. Fortunately, several solutions exist to diminish them and restore clearer skin. Is hyaluronic acid one of them? Find more information here about dilated pores and the potential effects of this macromolecule.

Summary
Published May 7, 2024, updated on May 7, 2024, by Pauline, Head of Scientific Communication — 5 min read

The effects of hyaluronic acid on enlarged pores?

The pores are small gaps present on the skin's surface that allow the flow of sweat and sebum. Normally almost invisible, they can dilate and become apparent, allowing impurities to settle and imperfections to form. This issue primarily affects oily skin, and pore dilation is often due to excessive sebum production, but it can also result from an accumulation of dead cells or the loosening of skin tissues. Indeed, the gradual decrease in collagen production is accompanied by a sagging of the skin structures. The pores then stretch and occupy an increasingly larger skin surface.

While AHA's such as glycolic acid and mandelic acid are very effective in reducing the visibility of pores, no scientific study shows that topical application of hyaluronic acid can act in this way. However, some recent studies have looked at the effects of this molecule when injected. Particularly known for their action on wrinkles, hyaluronic acid injections help to stimulate collagen synthesis in the dermis, which also influences pore dilation. Indeed, this firms up the skin structures and ensures the proper maintenance of the pore. However, hyaluronic acid cannot act on the two other causes of pore dilation: excessive sebum production and too rapid cell renewal. Moreover, the effects obtained are temporary and last between 6 and 24 months.

A preliminary study, conducted in 2017 by FAN and his team, involved 42 individuals seeking to reduce the visibility of their pores. Each participant received intra-dermal injections of 2.5 mL (25 mg) of low molecular weight hyaluronic acid across the entire face. This treatment was repeated two to five times with a one to one and a half month interval between injections. After 6 months, the average improvement in the participants' skin issues was evaluated at 40% using the Wilcoxon signed-rank test, a statistical test. Moreover, skin radiance and pigmentation were better after the treatment than before. No infections or nodules were reported at the injection sites, and patients only experienced temporary bruising. The satisfaction of the 42 subjects after 6 months was collected and is detailed in the table below.

Participants "very satisfied""Satisfied" ParticipantsParticipants "moderately satisfied""Dissatisfied" ParticipantsOverall Satisfaction Rate
17223092.8%

In 2021, JURAIRATTANAPORN and his team also explored the effects of hyaluronic acid injections on enlarged pores. They aimed to compare the effectiveness of micro-focused ultrasound alone versus micro-focused ultrasound combined with injections of cross-linked hyaluronic acid with low molecular weight. Quite popular in aesthetic medicine for skin tightening, micro-focused ultrasound generates a heating of the connective tissues, promoting the synthesis of collagen and elastin and the deposition of new hyaluronic acid fibers. 46 individuals participated in the study, each treated with micro-focused ultrasound across the entire face followed by an injection of 1 mL of hyaluronic acid on one half of the face.

Researchers have observed a significant reduction in pore size for both procedures. If we consider the following graph, it appears slightly more pronounced for micro-focused ultrasound followed by hyaluronic acid injection. However, even though error bars are absent from the graph, the authors indicated that the difference between the two was not significant. Therefore, it is impossible to assert that hyaluronic acid played a role. Regarding patient satisfaction, it was evaluated after 6 months at 6.84 ± 2.86 / 10 for monotherapy and at 7.41 ± 2.84 / 10 for the combined treatment. No side effects were reported, except for temporary bruising in two patients.

At present, we do not have enough perspective to attest to the effectiveness of hyaluronic acid injections on enlarged pores, as only one study has highlighted this property.

Évolution du volume moyen des pores et comparaison entre les ultrasons micro-focalisés seuls (MFU) ou suivis d'une injection d'acide hyaluronique (MFU + L-HA)
Evolution of average pore volume and comparison between micro-focused ultrasound alone (MFU) or followed by a hyaluronic acid injection (MFU + L-HA)
Source: JURAIRATTANAPORN N. & al. A study on the combined use of microfocused ultrasound and hyaluronic acid dermal filler for the treatment of enlarged facial pores in Asians. Journal of Cosmetic Dermatology (2021).

Sources

  • SEO S. J. & others. Facial pores: definition, causes, and treatment options.Dermatologic Surgery(2015).

  • GUTOWSKI K. Microfocused Ultrasound for Skin Tightening. Clinics in Plastic Surgery (2016).

  • FAN J. F. & al. Analysis of the effects of intradermal hyaluronic acid injections for the treatment of enlarged facial pores. Journal of Cosmetic Dermatology (2017).

  • JURAIRATTANAPORN N. & et al. A study on the combined use of microfocused ultrasound and hyaluronic acid dermal filler in the treatment of enlarged facial pores in Asians. Journal of Cosmetic Dermatology (2021).

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