It is always frustrating to see hair reappear just a few days after a waxing session, which explains the growing interest in hair regrowth‑inhibiting products, whether they are creams, lotions, serums designed to slow hair regrowth, or oils with anti-regrowth properties. These treatments, promoted as solutions capable of slowing hair growth, are theoretically based on a modulation of the hair cycle, more specifically on a prolongation of the telogen phase, or resting phase, or on a slowdown of the anagen phase, which corresponds to the active hair growth phase.
Some claims also put forward an effect on the very structure of the hair, in particular through an alteration of keratin synthesis, the main fibrous protein in hair produced by the keratinocytes of the hair follicle, which could lead to thinner, less pigmented, and potentially less visible hairs over successive cycles. Other hypotheses suggest an interaction with signaling pathways involved in the proliferation of matrix cells in the hair bulb, but these mechanisms remain largely speculative.
Despite a rapidly expanding market for hair regrowth-inhibiting products, scientific data remain limited.
Can wax tree extract slow down hair regrowth?
Often cited in hair regrowth-inhibiting care formulas, wax tree extract—more precisely, the insect wax secreted by Ericerus pela—is actually far from having demonstrated any inhibitory effect on hair growth. On the contrary, the available scientific data instead suggest a stimulatory effect on the hair follicle. In fact, some experimental studies show that topical application of this wax promotes the transition of the follicle from the telogen phase to the anagen phase. This stimulation is reportedly associated with an increase in the expression of the growth factor VEGF, thereby improving the supply of nutrients and oxygen needed for hair growth.
These observations were confirmed by an in vivo study conducted in mice, in which different concentrations of insect wax (30% and 45%) were applied to depilated skin areas, with comparison to a 5% minoxidil–based positive control, a drug used to treat alopecia. As early as day 16, visible hair regrowth was observed in the treated groups, unlike in the control group. Hair lengths measured in the 30% and 45% groups were significantly greater than those in the control group on days 16 and 20, with performance close to that of minoxidil. Histological analysis showed that this effect did not rely on the formation of new follicles, but rather on a premature conversion of existing follicles from the telogen phase to the anagen phase, as well as an extension of this growth phase. This activity is thought to be related in particular to increased expression of VEGF and to the presence of policosanols in the wax, identified as major active compounds.