Among the hair benefits attributed to rosemary essential oil, its potential to stimulate hair growth and prevent hair loss is drawing increasing interest. This effect is based on several mechanisms: a local action on microcirculation that enhances the delivery of nutrients and oxygen to the hair follicles, an indirect anti-inflammatory effect on the follicles, and an inhibitory activity on the androgenic pathway involved in hair loss.
Reminder: Androgenetic alopecia is primarily linked to the excessive conversion of testosterone into dihydrotestosterone (DHT) by the 5α-reductase enzyme. DHT binds to hair follicle receptors, disrupting their growth cycle and leading to progressive hair thinning.
Scientists assessed the effect of a hydroalcoholic rosemary extract on this mechanism. In a mouse model of testosterone-induced alopecia, daily application of 2 mg of rosemary extract led to a significant hair regrowth after 16 days of treatment. In vitro, this extract demonstrated marked inhibition of the 5α-reductase enzyme, as well as reduced binding of DHT to its receptors.
An active compound identified in the extract, the12-methoxy-sarcosalic acid, is partly responsible for this anti-androgenic activity.
Nevertheless, the results in human volunteers are more mixed. In a clinical study involving 100 men with androgenetic alopecia, 10% rosemary essential oil was compared to a 2% minoxidil solution, a drug known to promote hair growth. After six months of daily application, no change in hair count was observed in either group. Although the results for minoxidil, whose efficacy has been demonstrated in numerous other studies, were impressive, the same was true for rosemary essential oil.
Despite its promising potential to stimulate hair growth, rosemary essential oil still requires in-depth clinical studies.