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Quels sont les bienfaits des huiles sur le psoriasis ?

Psoriasis: Can Oils Help?

Psoriasis is an inflammatory skin disease that causes itching and pain in affected individuals. There are various methods that can be used to alleviate the symptoms of this disease. Do oils play a part in this? The answer is provided in this article.

Summary
Published February 20, 2024, by Manon, Scientific Editor — 5 min read

Are Psoriasis and Oils Compatible?

Psoriasis is a chronic inflammatory disease that primarily affects the skin and joints . It presents as red, thick patches that shed scales. Psoriasis is characterized by an excessive renewal and accumulation of epidermal cells, leading to local inflammation . Therefore, it is a relatively common disease, which is neither contagious nor of psychological origin.

Although psoriasis cannot be completely cured, it is possible to opt for natural solutions that soothe the skin from inflammation and itching caused by psoriasis and improve the quality of life of patients. Let's discover together which vegetable oils to favor to relieve psoriasis.

Borage oil.

Theborage oil is moisturizing. Thanks to its richness in omega-6 (linoleic acid) and omega-9 (oleic acid), it helps to maintain the hydrolipidic film. The abundance of borage oil in gamma-linolenic acid also gives it anti-inflammatory properties. Indeed, this acid is a precursor of type 1 prostaglandins and it is capable of inhibiting the production of pro-inflammatory mediators such as type 2 prostaglandins (PGE2) and leukotrienes. It is also capable of reducing the production of pro-inflammatory cytokines. Thus, borage oil helps to soothe itching and calm the skin.

The black seed oil.

Theblack seed oil contains thymoquinone, which gives it numerous pharmacological properties. Indeed, a study showed that in rats affected by IMQ-induced psoriasis, a cream containing black seed oil dosed at 5 mg/kg was able to reduce the severity score of psoriatic lesions. Specifically, thymoquinone helps to block the synthesis of certain pro-inflammatory cytokines, such as interleukins 2, 6, and 1β (IL-2, IL-6, and IL-1β), and limit the proliferation of keratinocytes. Moreover, thymoquinone has an inhibitory effect on the expression of cyclooxygenase (COX), an enzyme that catalyzes the conversion of arachidonic acid into prostaglandin H2. This latter is an inflammatory molecule that contributes to increasing itchiness.

Hemp oil.

Hemp oil possesses moisturizing properties due to its richness in omega 3, 6, and 9. These fatty acids protect the skin from dehydration by forming a film on the surface of the epidermis. Omega 3s also have anti-inflammatory properties by inhibiting the transcription factor NF-kB, thus preventing the release of pro-inflammatory mediators. This oil helps to soften your skin and prevent it from dehydration.

The jojoba oil.

Thejojoba oil is a friend to dry and dehydrated skin. Its richness in omega 6 and omega 9 allows it to strengthen the hydrolipidic film and form a protective layer to limit transepidermal water loss. A study has shown that jojoba oil has positive effects on psoriasis. This can be explained by its positive keratoplastic effect and its slight keratolytic effect to treat excessive skin flaking. However, its mode of action is not known.

Olive oil.

Theolive oil can be used for its nourishing and anti-inflammatory properties. Rich in omega 6 and omega 9, it strengthens the skin's barrier by preventing skin dehydration. The triterpenes found in olive oil speed up the healing process, especially in the case of micro-lesions. The phenolic compounds and vitamin E have antioxidant properties that protect the skin from external aggressions and promote cellular regeneration for the healing process. Thus, olive oil helps maintain your skin's hydration while promoting the healing process.

Flaxseed oil.

Flaxseed oil is composed of 50% omega-3 fatty acids. This composition allows it to form a protective film to combat transepidermal water loss. Its anti-inflammatory properties make this oil an ally in soothing skin from itching and irritations caused by psoriasis.

Sources

  • NYKTER M. & al. Quality characteristics of edible linseed oil. Agricultural and food science (2006).

  • ROSTAMI-YAZDI M. & al. Oxidative stress in the pathogenesis of psoriasis. Free radical biology and medicine (2009).

  • Lin TK, Zhong L, Santiago JL. Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. Int J Mol Sci. (2017).

  • ABDELASIS E. & al. Effect of Topical Application of Black Seed Oil on Imiquimod-Induced Psoriasis-like Lesions in the Thin Skin of Adult Male Albino Rats. Anatomical record (2018).

  • KIM B. & al. Black Cumin ( Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety. Nutrients (2021).

  • GAD H. A. & al. Jojoba Oil: An Updated Comprehensive Review on Chemistry, Pharmaceutical Uses, and Toxicity. Polymers (2021).

  • Mahdiyeh Taheri, Leila Amiri-Farahani, Anti-Inflammatory and Restorative Effects of Olives in Topical Application, Dermatology Research and Practice, (2021).

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