Vitamin E for good blood circulation?

First isolated in 1936, vitamin E is a fat-soluble vitamin that consists of a group of eight molecules: 4 tocopherols and 4 tocotrienols. Although it is not synthesized by the body, it is an essential nutrient for the body. Indeed, as an antioxidant, vitamin E has a protective role for the body and the skin by neutralizing free radicals before they can damage cells and organs. Vitamin E is primarily obtained through diet and is particularly present in vegetable oils (sunflower oil, olive oil...), nuts (walnuts, hazelnuts, almonds...) and seafood (mussels, shrimp...). Vitamin E is also found in various cosmetic products.

Beyond its major antioxidant function, vitamin E also plays a role in blood circulation. This molecule indeed has vasodilatory properties and is known to increase the production of nitric oxide (NO) by the endothelial cells of blood vessels. NO induces a relaxation of the smooth muscles of the vessels, which promotes blood flow. Furthermore, tocopherols inhibit the oxidation of LDL-cholesterol by free radicals, thus limiting the formation of atheroma plaques. These fatty plaques present on the walls of arteries hinder blood circulation and are the main cause of atherosclerosis, a disease that can quickly lead to life-threatening complications, such as heart failure or a stroke.

It has also been demonstrated that vitamin E can increase the production of vasodilator prostaglandins in the endothelial cells of the aorta. Belonging to the subfamily of eicosanoids, prostaglandins are lipids involved in the regulation of the inflammatory response. The biological mechanisms at work are still under study, but scientists suspect an effect of vitamin E on phospholipase A2 and on cyclooxygenase-2 (COX-2), enzymes involved in the synthesis of prostaglandins.

Finally, vitamin E enhances the membrane fluidity of red blood cells, which optimizes their deformability and circulation in the capillaries. This molecule also inhibits the release of thromboxane A2 (TXA2) by platelets, which are vasoconstrictors that induce platelet aggregation. In doing so, vitamin E limits the formation of clots and ensures a certain blood fluidity, essential for good cardiovascular health. Numerous epidemiological studies have indeed shown a link between a low dietary intake of vitamin E and the onset of coronary diseases.

Note : While the benefits of orally ingested vitamin E on blood circulation are well-documented, evidence is currently lacking regarding its effects when applied topically.