Profile: Azelaic Acid
Details
Properties
Antibacterial: Fighting against a variety of microorganisms, such as the bacteria Propionibacterium acnes which leads to acne;
Anti-inflammatory: Alleviate inflammatory reactions and reduce redness by inhibiting the expression of pro-inflammatory molecules (TNF-α, IL-1β, IL-6);
Depigmenting: Evening out the complexion by inhibiting tyrosinase, an enzyme involved in the process of melanogenesis;
Keratolytic: Decrease the thickness of the outer layers of dead cells by modulating the differentiation of keratinocytes;
Sebum Regulator: Decrease skin shine by normalizing the functional activity of the sebaceous glands through the inhibition of 5 α-reductase activity, an enzyme responsible for the conversion of testosterone into dihydrotestosterone, which can regulate sebum synthesis.
Applications
Facial Care (purifying cleansing gels, serums, moisturizing creams/gels/foams).
Preservation Method
Store in a dry place at room temperature, away from direct contact with light, heat, and humidity
Contraindications, Usage Precautions
Azelaic acid is compatible and well-tolerated by all skin types, posing no dangers to human health. However, it is still possible to experience some side effects (warmth, itching, redness, skin dryness, etc.) during the first use, which remain mild and infrequent.
Therefore, as a precautionary measure, it is recommended toperform a skin test before using any azelaic acid skincare product to observe potential adverse effects.
Due to its gentle nature, azelaic acid can be used safely in pregnant or breastfeeding women. However, we still advise discussing it with your doctor. On the other hand, its use is to be avoided in children due to the lack of concrete studies on these subjects.
Contrary to what its name might suggest, azelaic acid is not a photosensitizing agent. Therefore, it can be applied in the morning and/or evening.
