The tranexamic acid is a recently utilized active ingredient. Its scientifically proven brightening properties effectively combat hyperpigmentation, such as sun spots, melasma, or even acne marks. However, are there any adverse effects?
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The side effects of tranexamic acid.
Summary
- Tranexamic Acid, a new active ingredient to diminish pigmented spots
- What are the adverse effects of tranexamic acid in cosmetics?
- The anti-spot and firmness-lacking serum from Typology
- Source
Published April 26, 2022,
updated on July 17, 2024,
by
Maylis, Chemical Engineer
—
5 min read
Tranexamic Acid, a new active ingredient to diminish pigmented spots.
The tranexamic acid is a synthetic analogue of lysine. In the medical field, whether taken orally or by injection, tranexamic acid has been used for about fifty years for its anti-hemorrhagic properties. This molecule is even on the World Health Organization's (WHO) list of essential medicines.
In cosmetics, tranexamic acid has only been incorporated into certain treatments for about a decade. Studies have demonstrated its ability to control pigmentation by inhibiting the release of inflammatory mediators involved in triggering melanogenesis. Thus, it is effective in combating the three types of hyperpigmentation: the melasma caused by hormonal imbalances, the lentigo due to excessive and repeated sun exposure, and the post-inflammatory hyperpigmentation which results from an overproduction of melanin following inflammation (injuries, burns, blemishes, acne outbreaks).
What are the adverse effects of tranexamic acid in cosmetics?
Firstly, for it to be effective on pigmented spots, the concentration of tranexamic acid must be within 2 to 5% in a skincare product. Increasing its concentration does not enhance its effects but poses a risk of irritation.
The side effects of tranexamic acid in topical application were reported in a 2014 study that focused on the reduction of melasma using this molecule. The study indicates that the most common side effects are skin dryness, irritations , and sometimes increased peeling. To avoid this type of skin discomfort, it is recommended to apply a moisturizing cream following a tranexamic acid treatment.
If the skin tolerates this compound well from the start, a tranexamic acid skincare product can be used according to a frequency of twice a day,morning and evening (it is not photosensitizing ). On sensitive skin, its use will initially be limited to once a day, until the epidermis becomes accustomed to this new molecule.
It is important to note that if slight redness appears initially, it does not necessarily require the complete cessation of the use of a tranexamic acid skincare product.
However, in the event of excessive irritation or discomfort, immediately discontinue the use of the tranexamic acid skincare product.
The anti-spot and firmness-lacking serum from Typology.
The hyperpigmentation and firmness serum contains 5% tranexamic acid. This treatment reduces and prevents the appearance of pigmentation spots, particularly melasma, and promotes skin firming. The complexion is even, the skin is smoother and firmer. It also contains acetyl tetrapeptide-2, a peptide composed of four amino acids that stimulate the synthesis of key molecules involved in skin support and firmness: elastin, collagen, and fibrillin.
After applying this treatment, morning and evening, to counteract the slightly drying effect of tranexamic acid, you can use a face cream such as our nourishing face cream with hyaluronic acid and shea butter.
Source
EBRAHIMI B. & al. Topical tranexamic acid as a promising treatment for melasma. Journal of Research in Medical Sciences (2014).
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